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| Product Name: |
L-Lysine-S-Carboxy Methyl-L-Cysteine
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| Supply Ability: |
100mt |
| Related proudcts |
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| Specifications |
AJI92 |
| Price Term: |
fob |
| Port of loading: |
Ningbo |
| Minimum Order |
100kg |
| Unit Price: |
25 |
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Product name: L-Lysine-S-Carboxy Methyl-L-Cysteine
Synonyme: L-Carbocysteine-Lysine, SCMC-Lys
CAS#: 49673-81-6
Molecular Formula: C6H14N2O2.C5H9NO4S
Specification: 98%
Function:
Carbocysteine lysine salt monohydrate (SCMC-Lys) is a well-known mucoactive drug whose therapeutic efficacy is commonly related to the ability of SCMC-Lys to replace fucomucins by sialomucins. The aim of this study was to ***ermine if SCMC-Lys couldexert an anti-oxidant action by scavenging reactive oxygen intermediates (ROIs). Our results show that SCMC-Lys proved effective as a selective scavenger of hypochlorous acid (HOCl) and hydroxyl radical (OH.), this effect being related to the reactivity of the SCMC tioether group. The scavenger activity of SCMC-Lys was observed in free cellular system as well as in activated human polymorphonuclear neutrophils (PMNs). SCMC-Lys scavenger activity on HOCl was paralleled by a powerful protection from HOCl-mediated inactivation ofalpha1-antitripsin (alpha1-AT) inhibitor, the main serum protease inhibitor. Production of interleukin-(IL-)8, a major mediator of PMN recruitment in inflammatory diseases, is known to be mediated by intracellular OH.SCMC-Lys significantly reduced IL-8 production on stimulated human peripheral blood mononuclear cells (PBMCs) in the same range of concentrations affecting OH. activity. It is concluded that SCMC-Lys could exert, in addition to its mucoactive capacity, an anti-oxidant action, thus contributing to the therapeutic efficacy of SCMC-Lys.
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| Company: |
Ningbo Honor Chemtech Co.Ltd
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| Contact: |
Mr. will nieh |
| Address: |
Room404,12#, East Xintiandi |
| Postcode: |
315040 |
| Tel: |
+86-574-87336598 |
| Fax: |
+86-574-56118710 |
| E-mail: |
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